SPR inhibitor 3
Cat. No. :YN480641
CAS No. :1292285-54-1
86-020-82000279
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order@ubiochem.com| Product Name: | SPR inhibitor 3 |
| CAS NO.: | 1292285-54-1 |
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| Molecular Weight: | 262.30 |
| Molecular Formula: | C₁₄H₁₈N₂O₃ |
| SMILES: | O=C(NCCC1=C(C)NC2=C1C=C(O)C=C2)COC |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | SPR inhibitor 3 (SPRi3) is a potent sepiapterin reductase (SPR) inhibitor. SPR inhibitor 3 (SPRi3) displays high binding affinity to human SPR in a cell-free assay (IC50=74nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2μM). SPR inhibitor 3 (SPRi3) reduces neuropathic and inflammatory pain through a reduction of BH4 levels . |
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