Laflunimus
Cat. No. :YN320197
CAS No. :147076-36-6
86-020-82000279
sales@ubiochem.com
order@ubiochem.com| Product Name: | Laflunimus |
| CAS NO.: | 147076-36-6 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 310.27 |
| Molecular Formula: | C₁₅H₁₃F₃N₂O₂ |
| SMILES: | O=C(NC1=CC=C(C(F)(F)F)C(C)=C1)/C(C#N)=C(C2CC2)O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor ofdihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 µM for IgM and IgG, respectively. Laflunimus also is aprostagl and in endoperoxide H synthase (PGHS) -1 and -2inhibitor. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
TELL : +86-020-82000279
Add:Room 519, Block F, Guangzhou International Business Incubator, No.3 Lanyue Road, Science Town, Huangpu District, Guangzhou, China.
