CCR2 antagonist 4 hydrochloride
Cat. No. :YN320259
CAS No. :1313730-14-1
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Product Name: | CCR2 antagonist 4 hydrochloride |
CAS NO.: | 1313730-14-1 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 476.32 |
Molecular Formula: | C₂₁H₂₂Cl₂F₃N₃O₂ |
SMILES: | O=C(NCC(N[C@H]1CN(CC2=CC=C(Cl)C=C2)CC1)=O)C3=CC=CC(C(F)(F)F)=C3.[H]Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | CCR2 antagonist 4 hydrochloride (Teijin compound 1 hydrochloride) is a potent and specificCCR2antagonist, with IC50s of 180nM for CCR2b. CCR2 antagonist 4 hydrochloride potently inhibits MCP-1-induced chemotaxis with an IC50 of 24nM. |
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