2,5-Dihydroxyacetophenone
Cat. No. :YN350270
CAS No. :490-78-8
Pack size
price
inventory
100mg
$ 55.00
86-020-82000279
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order@ubiochem.com| Product Name: | 2,5-Dihydroxyacetophenone |
| CAS NO.: | 490-78-8 |
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| Molecular Weight: | 152.15 |
| Molecular Formula: | C₈H₈O₃ |
| SMILES: | CC(C1=CC(O)=CC=C1O)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | 2,5-Dihydroxyacetophenone possess anti-anxiety, and neuroprotective qualities. 2,5-Dihydroxyacetophenone treatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPKs, it also can potentiate the pro-apoptotic and anti-proliferative effects of bortezomib in U266 cells. 2,5-Dihydroxyacetophenone has anti-inflammatory activity in activated macrophages, raising the possibility that this compound has a therapeutic potential for inflammatory conditions. 2,5-Dihydroxyacetophenone is an uncompetitive inhibitor of murine tyrosinase (K(I) 0.28mm), it strongly inhibits both melanogenesis and cellular tyrosinase activity in vitro in 3-isobutyl-1-methylxanthin-stimulated B16 mouse melanoma cells or in vivo in zebrafish and mouse models. |
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