PF-00356231 hydrochloride
Cat. No. :YN370788
CAS No. :820223-77-6
86-020-82000279
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order@ubiochem.com| Product Name: | PF-00356231 hydrochloride |
| CAS NO.: | 820223-77-6 |
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| Molecular Weight: | 464.96 |
| Molecular Formula: | C₂₅H₂₁ClN₂O₃S |
| SMILES: | OC(C[C@H](C1=CC=CC=C1)NC(C2=CC(C3=CC=C(C4=CC=NC=C4)C=C3)=CS2)=O)=O.[H]Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating lig and and inhibitor of matrix metalloproteinaseMMP-12(IC50=1.4μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC50s of 0.00065, 1.7, 0.98, 0.39μM, respectively. |
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