FK706
Cat. No. :YN372533
CAS No. :144055-55-0
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order@ubiochem.com| Product Name: | FK706 |
| CAS NO.: | 144055-55-0 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 592.54 |
| Molecular Formula: | C₂₆H₃₂F₃N₄NaO₇ |
| SMILES: | O=C(NC(C(C)C)C(C(F)(F)F)=O)[C@H]1N(C([C@H](C(C)C)NC(C2=CC=C(C(NCC(O[Na])=O)=O)C=C2)=O)=O)CCC1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | FK706 is a potent, slow-binding and competitive inhibitor ofhuman neutrophil elastasewith an IC50 of 83nM and a Ki of 4.2nM. FK706 also inhibitsmouse neutrophil elastase and porcine pancreatic elastasewith IC50s of 22nM and 100nM, respectively, and has no inhibitory activity against other serine proteinases such as human pancreatic trypsin, human pancreatic α-chymotrypsin and human leukocyte cathepsin G. FK706 has anti-inflammatory effect. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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