Enoximone
Cat. No. :YN372932
CAS No. :77671-31-9
Product Name: | Enoximone |
CAS NO.: | 77671-31-9 |
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Molecular Weight: | 248.30 |
Molecular Formula: | C₁₂H₁₂N₂O₂S |
SMILES: | O=C1NC(C)=C(C(C2=CC=C(SC)C=C2)=O)N1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Enoximone is an inotropic vasodilating agent and a selective and orally activephosphodiesterase III (PDE3)inhibitor with an IC50 of 5.9μM. Enoximone induces vasodilatation and increases intracellular levels of cAMP by inhibiting cGMP-inhibited PDE. Enoximone also exhibitsPDE4inhibitory effect with an IC50 of 21.1μM formyocardial PDE4A. Enoximone has the potential for congestive heart failure research and has bronchodilatory, antiasthma and anti-inflammatory effects . |
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