Lanraplenib succinate
Cat. No. :YN440122
CAS No. :1800047-00-0
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Product Name: | Lanraplenib succinate |
CAS NO.: | 1800047-00-0 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 620.64 |
Molecular Formula: | C₂₃H₂₅N₉O.₃/₂C₄H₆O₄ |
SMILES: | NC1=CN=CC(C2=CN3C(C(NC4=CC=C(N5CCN(C6COC6)CC5)C=C4)=N2)=NC=C3)=N1.O=C(O)CCC(O)=O.[3/2] |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Lanraplenib succinate (GS-9876 succinate) is a highly selective and orally activeSYKinhibitor (IC50=9.5nM) in development for the treatment of inflammatory diseases. Lanraplenib succinate (GS-9876 succinate) inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans . |
IC50&Target: | |
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References: |
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