Sampatrilat
Cat. No. :YN370975
CAS No. :129981-36-8
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Product Name: | Sampatrilat |
CAS NO.: | 129981-36-8 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 584.68 |
Molecular Formula: | C₂₆H₄₀N₄O₉S |
SMILES: | OC([C@H](CNC([C@@H](NS(C)(=O)=O)CCCCN)=O)CC1(CCCC1)C(N[C@H](C(O)=O)CC2=CC=C(O)C=C2)=O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Sampatrilat (UK-81252) is a potent and orally activevasopeptidaseinhibitor ofACE and neutral endopeptidase (NEP). Sampatrilat inhibits C-domain ACE (Ki=13.8nM) 12.4-fold more potent than that for the N-domain (Ki=171.9nM). Sampatrilat (UK-81252) can be used for the study of chronic heart failure and blood pressure regulation. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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