Licoricidin
Cat. No. :YN373318
CAS No. :30508-27-1
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order@ubiochem.com| Product Name: | Licoricidin |
| CAS NO.: | 30508-27-1 |
| Chemical Name: | |
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| Molecular Weight: | 424.53 |
| Molecular Formula: | C₂₆H₃₂O₅ |
| SMILES: | COC1=C2C(OC[C@@H](C3=C(C(C/C=C(C)/C)=C(O)C=C3)O)C2)=CC(O)=C1C/C=C(C)/C |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Licoricidin (LCD) is isolated fromGlycyrrhiza uralensis Fisch, possesses anti-cancer activities. Licoricidin (LCD) inhibit SW480 cells (IC50=7.2μM) by inducing cycle arrest,apoptosis and autophagy, and is a potential chemopreventive or chemotherapeutic agent against colorectal cancer. Licoricidin (LCD) inhibits Lung Metastasis by inhibition of tumor angiogenesis and lymphangiogenesis as well as changes in the local microenvironment of tumor tissues the anticarcinogenic effect. Licoricidin enhanced gemcitabine-induced cytotoxicity in Osteosarcoma (OS) cells by inactivation of theAkt and NF-κBpathways in vitro and in vivo. Licoricidin blocks UVA-induced photoaging via ROS scavenging, limits the activity ofMMP-1, it can be considered as an active ingredient in new topically applied anti-ageing formulations. |
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