Ingenol 3,20-dibenzoate
Cat. No. :YN310240
CAS No. :59086-90-7
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order@ubiochem.com| Product Name: | Ingenol 3,20-dibenzoate |
| CAS NO.: | 59086-90-7 |
| Chemical Name: | |
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| Molecular Weight: | 556.65 |
| Molecular Formula: | C₃₄H₃₆O₇ |
| SMILES: | O[C@]([C@H]1OC(C2=CC=CC=C2)=O)([C@@H](C(COC(C3=CC=CC=C3)=O)=C4)O)[C@]([C@@H]5C)(C=C1C)C([C@H]4[C@@](C(C)6C)([H])[C@@]6([H])C5)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Ingenol 3,20-dibenzoate is a potentprotein kinase C (PKC)isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typicalapoptosisthrough de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-γ production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells. |
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