KRM-III
Cat. No. :YN481309
CAS No. :79220-94-3
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5mg
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Product Name: | KRM-III |
CAS NO.: | 79220-94-3 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 252.33 |
Molecular Formula: | C₁₅H₁₂N₂S |
SMILES: | S=C1NC(C2=CC=CC=C2)=CN1C3=CC=CC=C3 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | KRM-III is a potent and orally activeT-cell antigen receptor (TCR)inhibitor. KRM-III inhibitsTCR- and phorbol myristate acetate/ionomycin-induced activation of nuclear factor of activated T cells (NFAT) and T-cell proliferation with an IC50 of ~5μM. Anti-inflammatory activity. |
IC50&Target: | |
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Clinical Trial: | |
Solvent & Solubility: | |
References: |
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