RU.521
Cat. No. :YN330136
CAS No. :2262452-06-0
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order@ubiochem.com| Product Name: | RU.521 |
| CAS NO.: | 2262452-06-0 |
| Chemical Name: | |
| Synonyms: | RU320521 |
| Molecular Weight: | 415.23 |
| Molecular Formula: | C₁₉H₁₂Cl₂N₄O₃ |
| SMILES: | O=C1OC(C2=C(O)N(C3=NC4=CC=C(Cl)C(Cl)=C4N3)N=C2C)C5=C1C=CC=C5 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | RU.521 is an active, potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) that inhibits the cGAS-mediated signaling with IC50 of 700 nM. RU.521 binds to the cGAS/dsDNA complex with Kd of 36.2 nM. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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