BMS-986020
Cat. No. :YN320060
CAS No. :1257213-50-5
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order@ubiochem.com| Product Name: | BMS-986020 |
| CAS NO.: | 1257213-50-5 |
| Chemical Name: | |
| Synonyms: | AM152, AP-3152 free acid |
| Molecular Weight: | 482.53 |
| Molecular Formula: | C₂₉H₂₆N₂O₅ |
| SMILES: | O=C(C1(C2=CC=C(C3=CC=C(C4=C(NC(O[C@@H](C5=CC=CC=C5)C)=O)C(C)=NO4)C=C3)C=C2)CC1)O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | BMS-986020 (AM152, AP-3152 free acid) is a potent and selective antagonist of lysophosphatidic acid receptor 1 (LPA1). BMS-986020 inhibits bile acid and phospholipid transporters with IC50 of 4.8 μM, 6.2 μM, and 7.5 μM for BSEP, MRP4, and MDR3, respectively. BMS-986020 has the potential for the treatment of idiopathic pulmonary fibrosis (IPF). |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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