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AZD7545

Cat. No. :YN372377

  • CAS No. :252017-04-2

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    • Products Infomation
    • Biological Activity
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    • Product Name:AZD7545
      CAS NO.:252017-04-2
      Chemical Name:
      Synonyms:
      Molecular Weight:478.87
      Molecular Formula:C₁₉H₁₈ClF₃N₂O₅S
      SMILES:O=C(N(C)C)C1=CC=C(S(=O)(C2=CC=C(NC([C@@](C)(O)C(F)(F)F)=O)C(Cl)=C2)=O)C=C1
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:AZD7545 is a potent PDHK inhibitor with IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2, respectively. It failed to inhibit PDHK4 at higher concentrations(>10 nM), AZD7545 stimulates PDHK4 activity.
      IC50&Target:
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