PF-06409577
Cat. No. :YN420044
CAS No. :1467057-23-3
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Product Name: | PF-06409577 |
CAS NO.: | 1467057-23-3 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 341.79 |
Molecular Formula: | C₁₉H₁₆ClNO₃ |
SMILES: | O=C(C1=CNC2=C1C=C(C3=CC=C(C4(O)CCC4)C=C3)C(Cl)=C2)O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | PF-06409577 is orally bioavailable AMPK activator with EC50 of 7 nM for α1β1γ1 in the TR-FRET assay and it shows no detectable inhibition of hERG in a patch-clamp assay (100 μM) and was not an inhibitor (IC50 > 100 μM) of the microsomal activities of major human cytochrome P450 isoforms. |
IC50&Target: | |
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References: |
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