Omarigliptin
Cat. No. :YN372369
CAS No. :1226781-44-7
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5mg
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Product Name: | Omarigliptin |
CAS NO.: | 1226781-44-7 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 398.43 |
Molecular Formula: | C₁₇H₂₀F₂N₄O₃S |
SMILES: | N[C@@H]1[C@@H](C2=CC(F)=CC=C2F)OC[C@H](N3CC4=NN(S(=O)(C)=O)C=C4C3)C1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Omarigliptin (MK-3102) is a competitive, reversible inhibitor of DPP-4 (IC50 = 1.6 nM, Ki = 0.8 nM). It is highly selective over all proteases tested (IC50 > 67 μM), including QPP, FAP, PEP, DPP8, and DPP9 and has weak ion channel activity (IC50 > 30 μM at IKr, Caγ1.2, and Naγ1.5). |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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