Emixustat hydrochloride
Cat. No. :YN481681
CAS No. :1141934-97-5
Product Name: | Emixustat hydrochloride |
CAS NO.: | 1141934-97-5 |
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Molecular Weight: | 299.84 |
Molecular Formula: | C₁₆H₂₆ClNO₂ |
SMILES: | O[C@H](CCN)C1=CC(OCC2CCCCC2)=CC=C1.[H]Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3nM. Emixustat hydrochloride is a novel visual cycle modulator, in healthy volunteers. Oral Emixustat was safe and well tolerated when administered once daily for 14 days with minimal systemic adverse events reported. Evaluation of emixustat in subjects with geographic atrophy associated with dry age-related macular degeneration. |
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