BTRX-335140
Cat. No. :YN320599
CAS No. :2244614-14-8
86-020-82000279
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order@ubiochem.com| Product Name: | BTRX-335140 |
| CAS NO.: | 2244614-14-8 |
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| Molecular Weight: | 453.55 |
| Molecular Formula: | C₂₅H₃₂FN₅O₂ |
| SMILES: | CC1=NOC(C2=C(C)C3=CC(CC)=CC(F)=C3N=C2N4CCC(NC5CCOCC5)CC4)=N1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | BTRX-335140 (CYM-53093) is a potent and selective, orally activeκ opioid receptor (KOR)antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8nM, 110nM, and 6500nM, respectively. BTRX-335140 endows with favorable in vitro ADMET and in vivo pharmacokinetic profiles and medication-like duration of action in rats. BTRX-335140 can distribute well into the CNS. ADMET (absorption, distribution, metabolism, excretion, and toxicity). |
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