TP0463518
Cat. No. :YN370557
CAS No. :1558021-37-6
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order@ubiochem.com| Product Name: | TP0463518 |
| CAS NO.: | 1558021-37-6 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 431.83 |
| Molecular Formula: | C₂₀H₁₈ClN₃O₆ |
| SMILES: | ClC(C=C1)=CC=C1OC2=NC=C(CN3C(C(C(NCC(O)=O)=O)=C(O)CC3)=O)C=C2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with Ki of 5.3 nM for human PHD2. TP0463518 inhibits human PHD1, human PHD3 and monkey PHD2 with IC50 of 18 nM, 63 nM and 22 nM, respectively. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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