Sograzepide
Cat. No. :YN320919
CAS No. :155488-25-8
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order@ubiochem.com| Product Name: | Sograzepide |
| CAS NO.: | 155488-25-8 |
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| Molecular Weight: | 498.58 |
| Molecular Formula: | C₂₈H₃₀N₆O₃ |
| SMILES: | O=C(NC1=CC=CC(NC)=C1)N[C@H]2C(N(CC(C(C)(C)C)=O)C3=CC=CC=C3C(C4=NC=CC=C4)=N2)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Sograzepide (Netazepide; YF 476; YM-220) is an extremely potent , highly selective and orally activeGastrin/CCK-Bantagonist with an IC50 value of 0.1nM, has inhibitory effect on Gastrin/CCK-A activity with an IC50 of 502nM. Sograzepide (Netazepide; YF 476; YM-220) replaces the specific binding of [125I]CCK-8 to the rat brain, cloned canine and cloned human Gastrin/CCK-B receptors, with Ki values of 0.068, 0.62 and 0.19nM, respectively. |
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