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KML29

Cat. No. :YN372524

  • CAS No. :1380424-42-9

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    • Products Infomation
    • Biological Activity
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    • Product Name:KML29
      CAS NO.:1380424-42-9
      Chemical Name:
      Synonyms:
      Molecular Weight:549.42
      Molecular Formula:C₂₄H₂₁F₆NO₇
      SMILES:O=C(N1CCC(C(C2=CC=C(OCO3)C3=C2)(C4=CC=C(OCO5)C5=C4)O)CC1)OC(C(F)(F)F)C(F)(F)F
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:KML29 is an extremely selective, orally active and irreversibleMAGLinhibitor, with IC50 values of 15nM, 43nM and 5.9nM for mouse, rat and human MAGL, respectively. KML29 exhibits minimal cross-reactivity toward other central and peripheral serine hydrolases, including no detectable activity against FAAH.
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