LG100268
Cat. No. :YN372290
CAS No. :153559-76-3
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order@ubiochem.com| Product Name: | LG100268 |
| CAS NO.: | 153559-76-3 |
| Chemical Name: | |
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| Molecular Weight: | 363.49 |
| Molecular Formula: | C₂₄H₂₉NO₂ |
| SMILES: | O=C(C1=CC=C(C2(C3=C(C)C=C4C(C)(C)CCC(C)(C)C4=C3)CC2)N=C1)O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | LG100268 (LG268) is a potent, selective and orally activeretinoid X receptor (RXR)agonist withEC50values of 4nM, 3nM, and 4nM for RXR-α, RXR-β, and RXR-γ, respectively. LG100268 displays >1000-fold selectivity for RXR over RAR, theKivalues are 3.4nM, 6.2nM and 9.2nM for RXR-α, RXR-β, and RXR-γ, respectively. LG100268 activates RXR homodimers to induce transcriptional activation. LG100268 can be used for the study of lung carcinogenesisy. |
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