Ranirestat
Cat. No. :YN372287
CAS No. :147254-64-6
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order@ubiochem.com| Product Name: | Ranirestat |
| CAS NO.: | 147254-64-6 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 420.19 |
| Molecular Formula: | C₁₇H₁₁BrFN₃O₄ |
| SMILES: | O=C(N1CC2=CC=C(Br)C=C2F)C3=CC=CN3[C@]4(C(NC(C4)=O)=O)C1=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Ranirestat (AS-3201) potent and orally activealdose reductase (AR)inhibitor with IC50s of 11nM and 15nM forrat lens AR and recombinant human AR, respectively, and a Ki of 0.38nM forrecombinant human AR. Ranirestat has the potential for diabetic sensorimotor polyneuropathy treatment. Ranirestat also has a neuroprotective effect on diabetic retinas. |
| IC50&Target: | |
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