KL1333
Cat. No. :YN371181
CAS No. :1800405-30-4
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order@ubiochem.com| Product Name: | KL1333 |
| CAS NO.: | 1800405-30-4 |
| Chemical Name: | |
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| Molecular Weight: | 240.26 |
| Molecular Formula: | C₁₄H₁₂N₂O₂ |
| SMILES: | O=C(C1=C2N=C(C(C)C)N1)C(C3=C2C=CC=C3)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | KL1333, a derivative of β-lapachone, is an orally availableNAD+modulator. KL1333 reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. KL1333 protects against Cisplatin-induced ototoxicity in mouse cochlear cultures. |
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