Thiolutin
Cat. No. :YN251696
CAS No. :87-11-6
Pack size
price
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5mg
$ 450.00
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order@ubiochem.com| Product Name: | Thiolutin |
| CAS NO.: | 87-11-6 |
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| Molecular Weight: | 228.29 |
| Molecular Formula: | C₈H₈N₂O₂S₂ |
| SMILES: | CC(NC1=C2C(N(C)C1=O)=CSS2)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Thiolutin (Acetopyrrothin) is a disulfide-containing antibiotic and anti-angiogenic compound produced byStreptomyces. Thiolutin inhibits the JAMM metalloproteases Csn5, Associated-molecule-with-the-SH3-Domain-of-STAM (AMSH) and Brcc36. Thiolutin is a potent and selective inhibitor of endothelial cell adhesion accompanied by rapid induction of Heat-shock protein beta-1 (Hsp27) phosphorylation. |
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