Tesaglitazar
Cat. No. :YN290418
CAS No. :251565-85-2
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5mg
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Product Name: | Tesaglitazar |
CAS NO.: | 251565-85-2 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 408.47 |
Molecular Formula: | C₂₀H₂₄O₇S |
SMILES: | O=C(O)[C@@H](OCC)CC1=CC=C(OCCC2=CC=C(OS(=O)(C)=O)C=C2)C=C1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Tesaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist that is more potent on PPARγ than on PPARα, with EC50s of 13.4μM and 3.6μM for rat PPARα and human PPARα, respectively, and approximately 0.2μM for both rat and human PPARγ. Tesaglitazar induces interstitial mesenchymal cell DNA synthesis and fibrosarcomas in subcutaneous tissues in rats. |
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References: |
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