SBI-477
Cat. No. :YN480804
CAS No. :781628-99-7
Product Name: | SBI-477 |
CAS NO.: | 781628-99-7 |
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Molecular Weight: | 483.54 |
Molecular Formula: | C₂₄H₂₅N₃O₆S |
SMILES: | O=C(NC1=NC(C2=CC=C(OC)C=C2)=CS1)C3=CC=C(OCC(N4CCOCC4)=O)C(OC)=C3 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factorMondoA, leading to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain–containing 4 (ARRDC4). SBI-477 coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes. |
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