Verinurad
Cat. No. :YN360589
CAS No. :1352792-74-5
Product Name: | Verinurad |
CAS NO.: | 1352792-74-5 |
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Molecular Weight: | 348.42 |
Molecular Formula: | C₂₀H₁₆N₂O₂S |
SMILES: | CC(C)(SC1=C(C2=C3C=CC=CC3=C(C#N)C=C2)C=NC=C1)C(O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Verinurad (RDEA3170) is a high-affinity inhibitor of the URAT1 transporter with an IC50 of 25 nM for inhibiting transport activity of human URAT1. It inhibits the related URAT1 homologs OAT4 and OAT1 with approximately 200-fold lower affinity compared to URAT1 with IC50 values of 5.9 µM and 4.6 µM, respectively. |
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