BRD3308
Cat. No. :YN250811
CAS No. :1550053-02-5
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5mg
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Product Name: | BRD3308 |
CAS NO.: | 1550053-02-5 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 287.29 |
Molecular Formula: | C₁₅H₁₄FN₃O₂ |
SMILES: | O=C(C)NC1=CC=C(C(NC2=CC=C(F)C=C2N)=O)C=C1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | BRD3308 is a potant and highly selective inhibitor of HDAC3 with IC50 of 54 nM, 1.26 μM and 1.34 μM for HDAC3, HDAC1 and HDAC2, respectively. BRD3308 activates HIV-1 transcription. BRD3308 suppresses pancreatic β-cell apoptosis induced by inflammatory cytokines (glucolipotoxic stress) and increases functional insulin release. |
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References: |
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