GSK2945
Cat. No. :YN370849
CAS No. :1438071-12-5
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order@ubiochem.com| Product Name: | GSK2945 |
| CAS NO.: | 1438071-12-5 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 421.34 |
| Molecular Formula: | C₂₀H₁₈Cl₂N₂O₂S |
| SMILES: | O=[N+](C1=CC=C(CN(CC2=CC=C(Cl)C=C2C)CC3=CC=C(Cl)C=C3)S1)[O-] |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | GSK2945 is a class of tertiary amine, and is a highly specificRev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α)antagonist with EC50s of 21.5μM and 20.8μM, respectively. GSK2945 enhancescholesterol 7α-hydroxylase (CYP7A1)level and cholesterol metabolism. |
| IC50&Target: | |
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| In Vivo: | |
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| Solvent & Solubility: | |
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