4-Hydroxyisoleucine
Cat. No. :YN483405
CAS No. :781658-23-9
86-020-82000279
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order@ubiochem.com| Product Name: | 4-Hydroxyisoleucine |
| CAS NO.: | 781658-23-9 |
| Chemical Name: | |
| Synonyms: | (2S,3R)-2-Amino-4-hydroxy-3-methylpentanoic acid |
| Molecular Weight: | 147.17 |
| Molecular Formula: | C₆H₁₃NO₃ |
| SMILES: | N[C@@H]([C@@H](C)C(O)C)C(O)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | 4-Hydroxyisoleucine has beneficial effects on low-grade inflammation, it can reverse the insulin resistance by the activation of AMPK and suppression of SOCS-3 coimmunoprecipitation with both the IR-β subunit as well as IRS- 4-Hydroxyisoleucine acts to improve insulin resistance by promoting mitochondrial biogenesis in high fructose diet fed STZ induced diabetic rats. 4-Hydroxyisoleucine could remarkably improve high glucose-induced IR in 3T3-L1 adipocytes; could inhibit the secretion of TNF-alpha. 4-Hydroxyisoleucine has antidyslipidemic and antihyperglycemic effects. 4-Hydroxyisoleucine shows antidepressant-like effects in animal models of depression by brain serotonin turnover enhancement. |
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