MLi-2
Cat. No. :YN280003
CAS No. :1627091-47-7
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order@ubiochem.com| Product Name: | MLi-2 |
| CAS NO.: | 1627091-47-7 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 379.46 |
| Molecular Formula: | C₂₁H₂₅N₅O₂ |
| SMILES: | C[C@@](C1)([H])O[C@](C)([H])CN1C2=CC(C3=NNC4=CC=C(OC5(C)CC5)C=C43)=NC=N2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | MLi-2 is an orally active and highly selective inhibitor of LRRK2. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro with IC50 of 0.76 nM, a cellular assay monitoring dephosphorylation of LRRK2 pSer935 LRRK2 with IC50 of 1.4 nM, and a radioligand competition binding assay with IC50 of 3.4 nM. |
| IC50&Target: | |
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