PRE-084 hydrochloride
Cat. No. :YN321175
CAS No. :75136-54-8
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Product Name: | PRE-084 hydrochloride |
CAS NO.: | 75136-54-8 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 353.88 |
Molecular Formula: | C₁₉H₂₈ClNO₃ |
SMILES: | O=C(C1(C2=CC=CC=C2)CCCCC1)OCCN3CCOCC3.[H]Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | PRE-084 hydrochloride is a high affinity, selective σ1 agonist, has an IC50 of 44nM in the sigma receptor assay. IC50 value: 44nM in vitro: PRE-084 has an IC50 of more than 100,000nM for PCP receptors and an IC50 higher than 10,000nM in a variety of other receptor systems. in vivo: PRE-084 improves motor neuron survival and motor performance in wobbler mice. PRE-084 enhances BDNF-mediated trophic support. |
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