GW274150
Cat. No. :YN330175
CAS No. :210354-22-6
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order@ubiochem.com| Product Name: | GW274150 |
| CAS NO.: | 210354-22-6 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 219.30 |
| Molecular Formula: | C₈H₁₇N₃O₂S |
| SMILES: | N[C@@H](CCSCCNC(C)=N)C(O)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | GW274150 is a potent, selective, orally active and NADPH-dependent inhibitor of humaninducible nitric oxide synthase (iNOS)(IC50=2.19μM;Kd=40nM) and ratiNOS(ED50=1.15μM). GW274150 also displays less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS). GW274150 exerts a protective role in an acute model of lung injury inflammation. |
| IC50&Target: | |
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