PZ-2891
Cat. No. :YN480810
CAS No. :2170608-82-7
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order@ubiochem.com| Product Name: | PZ-2891 |
| CAS NO.: | 2170608-82-7 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 349.43 |
| Molecular Formula: | C₂₀H₂₃N₅O |
| SMILES: | N#CC1=NN=C(N2CCN(C(CC3=CC=C(C(C)C)C=C3)=O)CC2)C=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | PZ-2891 is a selective, orally active and brain-penetrant pantothenate kinase (PANK) modulator that acts as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits PANK with IC50 of 40.2 nM, 0.7 nM and 1.3 nM for hPANK1β, hPANK2, and hPANK3, respectively. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
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| Solvent & Solubility: | |
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