LP-935509
Cat. No. :YN480677
CAS No. :1454555-29-3
86-020-82000279
sales@ubiochem.com
order@ubiochem.com| Product Name: | LP-935509 |
| CAS NO.: | 1454555-29-3 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 396.44 |
| Molecular Formula: | C₂₀H₂₄N₆O₃ |
| SMILES: | O=C(N1CCN(C2=NC3=C(C4=CC=CN=C4OC)C=NN3C=C2)CC1)OC(C)C |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | LP-935509 is a selective, ATP-competitive and brain-penetrant inhibitor ofadapter protein-2 associated kinase 1 (AAK1)with an IC50 and a Ki of 3.3nM and 0.9nM, respectively. LP-935509 is also a potent inhibitor of BIKE (IC50=14nM) and a modest inhibitor of GAK (IC50=320nM). LP-935509 is highly brain-penetrant and reverses fully established pain behavior following the SNL procedure. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
TELL : +86-020-82000279
Add:Room 519, Block F, Guangzhou International Business Incubator, No.3 Lanyue Road, Science Town, Huangpu District, Guangzhou, China.
