Rheb inhibitor NR1
Cat. No. :YN420129
CAS No. :2216763-38-9
Pack size
price
inventory
5mg
$ 500.00
Product Name: | Rheb inhibitor NR1 |
CAS NO.: | 2216763-38-9 |
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Molecular Weight: | 578.30 |
Molecular Formula: | C₂₅H₁₉BrCl₂N₂O₃S |
SMILES: | O=C(C(N1CC2=CC=C(C(N(C)C)=O)C=C2)=CC3=C1C=C(SC4=CC=C(Cl)C(Cl)=C4)C=C3Br)O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Rheb inhibitor NR1 is aRhebinhibitor with an IC50 of 2.1 µM in the Rheb-IVK assay. Rheb inhibitor NR1 also is a selectivemTORC1inhibitor. NR1 inhibits the phosphorylation ofT389pS6K1 and increases the phosphorylation ofS473pAKT in a dose-dependent manner. |
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