EHNA hydrochloride
Cat. No. :YN370259
CAS No. :58337-38-5
Pack size
price
inventory
5mg
$ 250.00
Product Name: | EHNA hydrochloride |
CAS NO.: | 58337-38-5 |
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Molecular Weight: | 313.83 |
Molecular Formula: | C₁₄H₂₄ClN₅O |
SMILES: | CCCCCC[C@@](N1C2=C(C(N)=NC=N2)N=C1)([H])[C@H](O)C.[Relative stereochemistry].Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | EHNA hydrochloride is a potent and selective dual inhibitor ofcyclic nucleotide phosphodiesterase 2 (PDE2)(IC50=4μM) and adenosine deaminase (ADA). EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)(IC50:0.8μM (human), 2μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA hydrochloride play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects. |
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