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EHNA hydrochloride

Cat. No. :YN370259

  • CAS No. :58337-38-5

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    • Product Name:EHNA hydrochloride
      CAS NO.:58337-38-5
      Chemical Name:
      Synonyms:
      Molecular Weight:313.83
      Molecular Formula:C₁₄H₂₄ClN₅O
      SMILES:CCCCCC[C@@](N1C2=C(C(N)=NC=N2)N=C1)([H])[C@H](O)C.[Relative stereochemistry].Cl
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:EHNA hydrochloride is a potent and selective dual inhibitor ofcyclic nucleotide phosphodiesterase 2 (PDE2)(IC50=4μM) and adenosine deaminase (ADA). EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)(IC50:0.8μM (human), 2μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA hydrochloride play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects.
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