Aurintricarboxylic acid
Cat. No. :YN360325
CAS No. :4431-00-9
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Product Name: | Aurintricarboxylic acid |
CAS NO.: | 4431-00-9 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 422.34 |
Molecular Formula: | C₂₂H₁₄O₉ |
SMILES: | O=C(C=C/1)C(C(O)=O)=CC1=C(C2=CC(C(O)=O)=C(O)C=C2)C3=CC(C(O)=O)=C(O)C=C3 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitiveP2X1Rs and P2X3Rs, with IC50s of 8.6nM and 72.9nM for rP2X1R and rP2X3R, respectively. Aurintricarboxylic acid is a potent anti-influenza agent by directly inhibiting theneuraminidase. Aurintricarboxylic acid is an inhibitor oftopoisomerase II and apoptosis. Aurintricarboxylic acid is a selective inhibitor of theTWEAK-Fn14signaling pathway.Aurintricarboxylic acid also acts as acystathionine-lyase (CSE)inhibitor with an IC50 of 0.6μM.. |
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