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JNJ-54175446

Cat. No. :YN360298

  • CAS No. :1627902-21-9

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    • Product Name:JNJ-54175446
      CAS NO.:1627902-21-9
      Chemical Name:
      Synonyms:
      Molecular Weight:440.78
      Molecular Formula:C₁₈H₁₃ClF₄N₆O
      SMILES:ClC1=C(C=CC=C1C(N2CCC3=C(N=NN3C4=NC=C(F)C=N4)[C@H]2C)=O)C(F)(F)F
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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      Purity:
    • Description:JNJ-54175446 is a potent and selective brain penetrantP2X7 receptorantagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively.
      IC50&Target:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
      References:
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