P2X3 antagonist 34
Cat. No. :YN360441
CAS No. :2417288-67-4
86-020-82000279
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order@ubiochem.com| Product Name: | P2X3 antagonist 34 |
| CAS NO.: | 2417288-67-4 |
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| Molecular Weight: | 456.49 |
| Molecular Formula: | C₂₄H₂₆F₂N₄O₃ |
| SMILES: | O=C(OC)N1C[C@@H](CCC1)CC2=C(N=C3C=C(C=CN32)C)C4=C(C=C(C=C4F)C(NC)=O)F |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | P2X3 antagonist 34 is a potent, selective and orally activeP2X3 homotrimeric receptorantagonist with IC50s of 25 nM, 92 nM and 126 nM forhuman P2X3,rat P2X3 and guinea pig P2X3 receptors, respectively. P2X3 antagonist 34 is less active against human, rat and guinea pig P2X2/3 heterotrimeric receptors. P2X3 antagonist 34 has strong anti-tussive effect. |
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