Paxilline
Cat. No. :YN361005
CAS No. :57186-25-1
86-020-82000279
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order@ubiochem.com| Product Name: | Paxilline |
| CAS NO.: | 57186-25-1 |
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| Molecular Weight: | 435.56 |
| Molecular Formula: | C₂₇H₃₃NO₄ |
| SMILES: | O=C1[C@@H](C(C)(O)C)O[C@](CC2)([H])C([C@]([C@@]2(C)[C@]34C)(O)CC[C@@]3([H])CC5=C4NC6=C5C=CC=C6)=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Paxilline is an indole alkaloid mycotoxin fromPenicillium paxilli, acts as a potentBK channelsinhibitor by an almost exclusively closed-channel block mechanism. Paxilline also inhibits thesarco/endoplasmic reticulum Ca2+ATPase (SERCA)with IC50s between 5μM and 50μM for differing isoforms. Paxilline possesses significant anticonvulsant activity . |
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