FG 7142
Cat. No. :YN360063
CAS No. :78538-74-6
86-020-82000279
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order@ubiochem.com| Product Name: | FG 7142 |
| CAS NO.: | 78538-74-6 |
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| Molecular Weight: | 225.25 |
| Molecular Formula: | C₁₃H₁₁N₃O |
| SMILES: | O=C(C1=CC2=C(C=N1)NC3=C2C=CC=C3)NC |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor(Ki=91nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137nM). FG 7142 (ZK 39106; LSU-65) can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. |
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