(Rac)-Tavapadon
Cat. No. :YN1730042
CAS No. :1643462-64-9
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Product Name: | (Rac)-Tavapadon |
CAS NO.: | 1643462-64-9 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 391.34 |
Molecular Formula: | C₁₉H₁₆F₃N₃O₃ |
SMILES: | O=C1NC(C(C)=C(C2=CC=C(OC3=NC=CC=C3C(F)(F)F)C=C2C)N1C)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | (Rac)-Tavapadon ((Rac)-PF-06649751) is a potent and selective noncatecholdopamine D1 receptoragonist. (Rac)-Tavapadon displays potent full agonism in the GS activation assay as well as partial agonism in the β-arrestin2 recruitment assay (GS-cAMP, EC50=0.8nM; β-arrestin2, EC50=68nM). (Rac)-Tavapadon has antiparkinsonian activity. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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