Spinosin
Cat. No. :YN482513
CAS No. :72063-39-9
86-020-82000279
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order@ubiochem.com| Product Name: | Spinosin |
| CAS NO.: | 72063-39-9 |
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| Molecular Weight: | 608.54 |
| Molecular Formula: | C₂₈H₃₂O₁₅ |
| SMILES: | COC1=C([C@H](O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H]2O[C@]([C@@H]([C@@H](O)[C@@H]3O)O)([H])O[C@@H]3CO)C(O)=C4C(OC(C5=CC=C(O)C=C5)=CC4=O)=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Spinosin ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. Spinosin exerts anxiolytic-like effects, and its mechanism of action appears to be modulated by GABAA and 5-HT1A receptors. There was a wide brain regional tissue distribution of Spinosin. The concentrations of Spinosin in corpus striatum and hippocampus were higher than that in other areas. Spinosin can potentiate pentobarbital-induced sleep via the serotonergic system. Spinosin has inhibitory effect on 8-OH-DPAT-induced hypothermia and has potentiating effect on pentobarbital-induced loss of righting reflex (LORR) in mice,presynaptic 5-HT(1A) autoreceptor mechanisms may be involved in the effects. |
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