THPP-1
Cat. No. :YN370859
CAS No. :1257051-63-0
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5mg
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Product Name: | THPP-1 |
CAS NO.: | 1257051-63-0 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 464.90 |
Molecular Formula: | C₂₃H₂₁ClN₆O₃ |
SMILES: | O=C(C1=C2C=CC=CN2C=N1)N3CCC4=NC(C5=CC=C(N=C5)Cl)=NC(OCCOC)=C4C3 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | THPP-1, a SGC chemical probe, is a potent and orally bioavailablephosphodiesterase 10A (PDE10A)inhibitor, with Ki values of 1nM and 1.3nM for human and rat PDE10A, respectively. THPP-1 has excellent pharmacokinetic properties in preclinical species. |
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Clinical Trial: | |
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References: |
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