ML417
Cat. No. :YN1730059
CAS No. :1386162-69-1
86-020-82000279
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order@ubiochem.com| Product Name: | ML417 |
| CAS NO.: | 1386162-69-1 |
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| Molecular Weight: | 379.45 |
| Molecular Formula: | C₂₂H₂₅N₃O₃ |
| SMILES: | O=C(C(N1)=CC2=C1C=CC=C2)N3CCN(CCOC4=CC=C(OC)C=C4)CC3 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | ML417 is a selective and brain penetrantD3 dopamine receptor (D3R)agonist, with an EC50 of 38nM. ML417 potently promotes D3R-mediated β-arrestin translocation, G protein mediated signaling, and pERK phosphorylation with minimal effects on other GPCR-mediated signaling. ML417 exhibits neuroprotection against toxin-induced neurodegeneration of dopaminergic neurons. |
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