LP-922761
Cat. No. :YN480723
CAS No. :1454808-95-7
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Product Name: | LP-922761 |
CAS NO.: | 1454808-95-7 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 410.47 |
Molecular Formula: | C₂₁H₂₆N₆O₃ |
SMILES: | O=C(N(C)CCNC1=NN2C(C=C1)=NC=C2C3=CC=C(C=C3)C(N)=O)OC(C)(C)C |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | LP-922761 is a potent, selective and orally activeadapter protein-2 associated kinase 1 (AAK1) inhibitor with IC50s of 4.8nM and 7.6nM in enzyme and cell assays, respectively. LP-922761 also inhibitsBMP-2-inducible protein kinase (BIKE)with an IC50 of 24nM. LP-922761 exhibits no significant activity at cyclin G-associated kinase (GAK), opioid, adrenergic α2 or GABAa receptors. |
IC50&Target: | |
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References: |
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