Smilagenin
Cat. No. :YN320303
CAS No. :126-18-1
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Product Name: | Smilagenin |
CAS NO.: | 126-18-1 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 416.64 |
Molecular Formula: | C₂₇H₄₄O₃ |
SMILES: | C[C@@H]1[C@@]2(CC[C@@H](C)CO2)O[C@]3([H])[C@@]1([H])[C@@]4([C@@]([C@@]5([H])[C@]([C@@]6([C@](C[C@@H](O)CC6)([H])CC5)C)([H])CC4)([H])C3)C |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Smilagenin (SMI) is a lipid-soluble small-molecule steroidal sapogenin fromRhizoma anemarrhenae and Radix asparagiwidely used in traditional Chinese medicine for treating chronic neurodegeneration diseases. Smilagenin (SMI) improves memory of aged rats by increasing the muscarinic receptor subtype 1 (M1)-receptor density. Smilagenin (SMI) attenuates Aβ(25-35)-induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD. |
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